← All Peptides

Sermorelin

GH decline, sleep quality

The OG of GH peptides. Originally FDA-approved in 1997 (Geref), later withdrawn from US market for commercial reasons — still available via compounding pharmacies.

In Plain English

The GH peptide with the longest clinical history. Used for decades in research and hormone clinics. Less potent than newer options but the most data behind it.

What Researchers Have Studied It For

+Longest clinical history
+Natural GH stimulation
+Deep sleep
+Age-related GH decline
+Lean body mass
Molecular Weight
3358 Da
Half-Life
~10–20 minutes
Source
First 29 amino acids of GHRH
Storage
Keep frozen as powder. Refrigerate once mixed.
Category
Growth Hormone

Published Research

Sermorelin for adult GH insufficiency
Clin Interv Aging (2012)

You might also look at

CJC-1295 No DAC

As you age, your GH pulses weaken. This peptide turns up the volume without flooding your system.

GH optimization, sleep

CJC-1295 with DAC

Same idea but stays active 6-8 days instead of hours. Simpler dosing, less natural pulsing.

Sustained GH elevation

Ipamorelin

Most GH peptides have side effects. Ipamorelin is the exception — boosts GH cleanly without messing with stress hormones

Clean GH boost, sleep

Tesamorelin

FDA-approved to shrink dangerous belly fat. Also studied for brain health and liver fat. The gold standard.

Belly fat, metabolic health
Research-use disclaimer — Sermorelin is referenced here for research education only. It is not approved by the FDA for human consumption, treatment, cure, or diagnosis of any condition. Nothing on this page is medical advice. Consult a licensed physician for anything related to your health.