← All Peptides

NAD+

Energy, aging, brain fog

A coenzyme that drops 50% by middle age. Low NAD+ means low energy, poor DNA repair, faster aging.

In Plain English

NAD+ is fuel for your cells' repair machinery. When it drops with age, everything starts breaking down faster.

B / C

At a glance

Not a peptide. Pills your body converts are cheaper and better studied. Evidence grade B / C on an A-to-D scale.

HOW IT IS TAKEN
Under the skin, or IV drip in clinics
HOW OFTEN
Daily to a few times a week
HOW LONG
Weeks
TESTED SPORT
Not banned

Reported practice from trials and the community, not a recommendation for anyone.

What Researchers Have Studied It For

+Cellular energy
+DNA repair
+Longevity gene activation
+Brain function
+Metabolism

Studied for

Anti-Aging
Molecular Weight
663 Da
Half-Life
~9 hours (systemic)
Source
Coenzyme (not a peptide)
Storage
Keep frozen as powder. Refrigerate once mixed.
Category
Longevity

Published Research

NAD+ repletion improves mitochondrial function
Science (2016)

Common questions about NAD+

What is NAD+ used for?

Researchers have studied NAD+ for cellular energy, dna repair, longevity gene activation, and more. In plain terms: NAD+ is fuel for your cells' repair machinery. When it drops with age, everything starts breaking down faster.

Is NAD+ FDA-approved?

It is not a drug in the usual sense; it is a molecule every cell makes. Injected and infused NAD+ is sold by clinics with very little controlled evidence behind it.

How is NAD+ usually taken?

The commonly reported pattern is under the skin, or IV drip in clinics, daily to a few times a week, for weeks. That describes reported practice from trials and the community. It is not a recommendation for anyone, and several of these compounds interact with common medications.

How strong is the evidence for NAD+?

Grade B / C on this site's A-to-D scale. B means tested in people, but not approved for the use people buy it for. Not a peptide. Pills your body converts are cheaper and better studied.

Is NAD+ banned in drug-tested sport?

It is not specifically listed by the World Anti-Doping Agency, but tested athletes should check the current list and their federation's rules, since related compounds and blends often are.

How long does NAD+ stay in the body?

The half-life, the time for half a dose to leave the body, is about ~9 hours (systemic). A short half-life means it wears off fast and is taken more often; a long one means once a week can be enough. Stored as a dry powder it keeps for months in the fridge; once mixed with water it is used within a few weeks.

🎓
Go deeper on NAD+ in The Peptide Course
How people commonly use it, what they notice, side effects, who stays away, and how good the evidence really is. Plus how to buy a vial that is actually NAD+, and how to mix it. Six lessons are free.
Open the lesson →

You might also look at

GHK-Cu

Your skin made tons of this when you were young. By 60, you have almost none. Research shows it restarts collagen produc

Skin, hair, anti-aging

SS-31

As you age, your cells' engines break down and you lose energy. SS-31 is like a mechanic that fixes each cell's engine f

Energy, cellular aging

Epithalon

Your DNA has protective caps that get shorter every time cells divide. Epithalon may help rebuild them.

Aging, sleep, telomeres

MOTS-c

Your body releases MOTS-c when you exercise. It helps burn fat and improve insulin sensitivity — even without the gym.

Metabolism, fitness, aging
Research-use disclaimer — NAD+ is referenced here for research education only. It is not approved by the FDA for human consumption, treatment, cure, or diagnosis of any condition. Nothing on this page is medical advice. Consult a licensed physician for anything related to your health.