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SS-31

Energy, cellular aging

Goes directly into your mitochondria and repairs them. One of few peptides in human clinical trials.

In Plain English

As you age, your cells' engines break down and you lose energy. SS-31 is like a mechanic that fixes each cell's engine from the inside.

A / B

At a glance

Approved in 2025 for one rare disease. Unproven in healthy people. Evidence grade A / B on an A-to-D scale.

HOW IT IS TAKEN
Under the skin
HOW OFTEN
Daily
HOW LONG
4 to 8 weeks
TESTED SPORT
Not banned

Reported practice from trials and the community, not a recommendation for anyone.

What Researchers Have Studied It For

+Mitochondrial repair
+Cellular energy
+Heart function
+Kidney protection
+Exercise performance

Studied for

Anti-Aging
Molecular Weight
641 Da
Half-Life
~2.5 hours
Source
4 amino acids targeting mitochondria
Storage
Keep frozen as powder. Refrigerate once mixed.
Category
Longevity

Published Research

Elamipretide in Barth syndrome trial
Genet Med (2021)

Common questions about SS-31

What is SS-31 used for?

Researchers have studied SS-31 for mitochondrial repair, cellular energy, heart function, and more. In plain terms: As you age, your cells' engines break down and you lose energy. SS-31 is like a mechanic that fixes each cell's engine from the inside.

Is SS-31 FDA-approved?

Yes, as of 2025, for Barth syndrome, a rare inherited mitochondrial disease. Its use for general aging or performance is unproven.

How is SS-31 usually taken?

The commonly reported pattern is under the skin, daily, for 4 to 8 weeks. That describes reported practice from trials and the community. It is not a recommendation for anyone, and several of these compounds interact with common medications.

How strong is the evidence for SS-31?

Grade A / B on this site's A-to-D scale. A means approved as a medicine somewhere, with large controlled trials behind that use. Approved in 2025 for one rare disease. Unproven in healthy people.

Is SS-31 banned in drug-tested sport?

It is not specifically listed by the World Anti-Doping Agency, but tested athletes should check the current list and their federation's rules, since related compounds and blends often are.

How long does SS-31 stay in the body?

The half-life, the time for half a dose to leave the body, is about ~2.5 hours. A short half-life means it wears off fast and is taken more often; a long one means once a week can be enough. Stored as a dry powder it keeps for months in the fridge; once mixed with water it is used within a few weeks.

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Go deeper on SS-31 in The Peptide Course
How people commonly use it, what they notice, side effects, who stays away, and how good the evidence really is. Plus how to buy a vial that is actually SS-31, and how to mix it. Six lessons are free.
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Research-use disclaimer — SS-31 is referenced here for research education only. It is not approved by the FDA for human consumption, treatment, cure, or diagnosis of any condition. Nothing on this page is medical advice. Consult a licensed physician for anything related to your health.